A recent study published in Nature Geoscience uses supercomputer climate models to examine how a supercontinent, dubbed Pangea Ultima (also called Pangea Proxima), that will form 250 million years from now will result in extreme temperatures, making this new supercontinent uninhabitable for life, specifically mammals.
Pangaea Proxima is just one of four possible future supercontinents. There are others where for example the Atlantic continues to grow and the Americas drift into Asia.