https://dndi.org/press-releases/2023/worlds-first-clinical-trial-for-mycetoma-shows-efficacy-new-promising-treatment/
This is based on pre-publish results from a phase II randomized-controlled trial comparing fosravuconazole and itraconazole.
It’s odd that the 300 mg dose would perform worse than 200 mg, but it could be due to randomness; they don’t give the sample size or ratio of bacterial vs fungal infection. Hopefully I remember to check back in a few weeks to read the published paper
https://dndi.org/press-releases/2023/worlds-first-clinical-trial-for-mycetoma-shows-efficacy-new-promising-treatment/ This is based on pre-publish results from a phase II randomized-controlled trial comparing fosravuconazole and itraconazole. It’s odd that the 300 mg dose would perform worse than 200 mg, but it could be due to randomness; they don’t give the sample size or ratio of bacterial vs fungal infection. Hopefully I remember to check back in a few weeks to read the published paper